Great atmosphere with hand crafted beers

We craft our own beers! Sometimes we even play our own music.

    What's On Tap

    With over 20 taps at our main bar, you're sure to find something you like!

    Try a Flight

    Try a sample of our signature brews. Four samples of your choice.

    Friendly Faces and Great Beer

    Our knowledgeable staff can answer any questions you have about how our beers are crafted.

    Beer Garden

    Take our beer outside and enjoy Southern Illinois at its finest.

    Live Music

    Enjoy live music while you drink and dance the night away!

    Discover what all the buzz is about!

    Route 51 Beer Menu

    We are constantly brewing new beers so check back to see what's new.

    See what's

    Route 51 Events

    Banquet Center

    Need Space?

    Route 51 Brewery has a 6,400 square foot banquet hall that can seat 299 people, making this the best place for your event.

    Any Occasion

    We're perfect for receptions, holiday parties, baby showers, bridal showers, class reunions, corporate events, or any other occasion.

    Private Bar

    You'll have your own private, 32 ft. granite bar and it comes fully stocked and has 6 taps available.

    Book Now!

    If you have any questions regarding pricing or additional details, just give us a call. Contact us at 618-568-2739.

    We new friends!


    Monday Closed
    Tuesday Closed
    Wednesday Closed
    Thursday 4:00pm - 9:00pm
    Friday 4:00pm - 10:00pm
    Saturday 12:00pm - 10:00pm
    Sunday 12:00pm - 5:00pm